Chemistry:CY-208,243
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Short description: Chemical compound
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| Formula | C19H18N2 |
| Molar mass | 274.367 g·mol−1 |
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CY-208,243 is a drug which acts as a dopamine agonist selective for the D1 subtype. Unlike most D1-selective agonists, it shows efficacy in animal models of Parkinson's disease.[1][2][3][4][5]
References
- ↑ "Effect of adding the D-1 agonist CY 208-243 to chronic bromocriptine treatment of MPTP-monkeys: regional changes of brain dopamine receptors". Progress in Neuro-psychopharmacology & Biological Psychiatry 19 (4): 667–76. July 1995. doi:10.1016/0278-5846(95)00110-h. PMID 8588064.
- ↑ "Dopamine D1-like receptor agonists impair responding for conditioned reward in rats". Behavioural Pharmacology 6 (8): 785–793. December 1995. doi:10.1097/00008877-199512000-00003. PMID 11224381.
- ↑ "Pulsatile administration of D1 but not D2 dopamine agonists induces behavioral tolerance in MPTP-treated monkeys". Advances in Neurology 69: 239–44. 1996. PMID 8615134.
- ↑ "Dopamine D1 receptor agonists induce penile erections in rats". European Journal of Pharmacology 460 (1): 71–4. January 2003. doi:10.1016/S0014-2999(02)02881-9. PMID 12535862.
- ↑ "Dopamine agonists suppress cholinomimetic-induced tremulous jaw movements in an animal model of Parkinsonism: tremorolytic effects of pergolide, ropinirole and CY 208-243". Behavioural Brain Research 156 (2): 173–9. January 2005. doi:10.1016/j.bbr.2004.05.019. PMID 15582103.
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