Chemistry:Desmethoxyfallypride
From HandWiki
Short description: Chemical compound
 | |
| Clinical data | |
|---|---|
| Other names | DMFP (18F) |
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C19H27FN2O2 |
| Molar mass | 334.435 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Desmethoxyfallypride is a moderate affinity dopamine D2 receptor/D3 receptor antagonist used in medical research, usually in the form of the radiopharmaceutical [F-18]-desmethoxyfallypride (DMFP(18F))[1][2] which has been used in human studies as a positron emission tomography (PET) radiotracer.[3][4]
References
- ↑ "18F-desmethoxyfallypride: a fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for PET imaging studies of dopamine D2 receptors". Life Sciences 59 (8): 669–78. 1996. doi:10.1016/0024-3205(96)00348-7. PMID 8761017.
- ↑ Leung, K. (2004). "(S)-N-((1-Allyl-2-pyrrolidinyl)methyl)-5-(3-[18F]fluoropropyl)-2-methoxybenzamide". Molecular Imaging and Contrast Agent Database. PMID 20641474.
- ↑ "Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride". Journal of Nuclear Medicine 44 (1): 109–16. January 2003. PMID 12515884.
- ↑ "Parametric mapping of binding in human brain of D2 receptor ligands of different affinities". Journal of Nuclear Medicine 46 (6): 964–72. June 2005. PMID 15937307.
 |  |
