Chemistry:CP-226,269

CP-226,269
Identifiers
	IUPAC name 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole;
CAS Number	220941-93-5 ;
PubChem CID	9796720;
IUPHAR/BPS	973;
ChemSpider	7972486 ;
UNII	WX4CVT9DYH;
ChEMBL	ChEMBL77395 ;
Chemical and physical data
Formula	C18H19FN4
Molar mass	310.376 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES n4ccccc4N3CCN(CC3)Cc2cc1cc(F)ccc1[nH]2;
	InChI InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 ; Key:PQOIDBZLMJMYCD-UHFFFAOYSA-N ;
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Short description: Chemical compound

CP-226,269 is a drug which acts as a dopamine agonist selective for the D₄ subtype, which is used for researching the role of D₄ receptors in the brain.^[1]^[2]

References

↑ "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry 4 (3): 235–46. May 1999. doi:10.1038/sj.mp.4000522. PMID 10395213.
↑ "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology 30 (7): 1257–68. July 2005. doi:10.1038/sj.npp.1300677. PMID 15688083.

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Original source: https://en.wikipedia.org/wiki/CP-226,269. Read more

[pmid10395213-1] "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry 4 (3): 235–46. May 1999. doi:10.1038/sj.mp.4000522. PMID 10395213.

[pmid15688083-2] "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology 30 (7): 1257–68. July 2005. doi:10.1038/sj.npp.1300677. PMID 15688083.

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Identifiers


IUPAC name 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole
CAS Number	220941-93-5^N
PubChem CID	9796720
IUPHAR/BPS	973
ChemSpider	7972486^Y
UNII	WX4CVT9DYH
ChEMBL	ChEMBL77395^Y
Chemical and physical data
Formula	C₁₈H₁₉FN₄
Molar mass	310.376 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES n4ccccc4N3CCN(CC3)Cc2cc1cc(F)ccc1[nH]2
InChI InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2^Y Key:PQOIDBZLMJMYCD-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

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