Chemistry:GSK-789,472

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GSK-789,472
GSK-789,472.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
Chemical and physical data
FormulaC15H21N3O
Molar mass259.353 g·mol−1
3D model (JSmol)
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GSK-789,472 is a drug which acts as both a potent and selective partial agonist at the dopamine receptor D2, as well as an antagonist at the related D3 subtype, but with good selectivity over D4 and other unrelated receptors.[1]

References

  1. "The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure". Bioorganic & Medicinal Chemistry Letters 20 (6): 2013–6. March 2010. doi:10.1016/j.bmcl.2010.01.090. PMID 20153647.