Chemistry:CJ-1639

From HandWiki

CJ-1639 is a drug derived from pramipexole, which acts as a highly potent and selective full agonist for the dopamine D3 receptor. It has a Ki of 3.61 nM and is over 1000x selective for D3 over the D1 and D2 receptors.[1]

References

  1. ↑ "CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist". ACS Medicinal Chemistry Letters 2 (8): 620–625. August 2011. doi:10.1021/ml200100t. PMID 22125662. 



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