Chemistry:RDS-127
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Short description: Chemical compound
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| Formula | C17H27NO2 |
| Molar mass | 277.408 g·mol−1 |
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RDS-127 is a drug which is used in scientific research. It acts as a D2-like receptor agonist[1] and also has some serotonin and adrenergic agonist effects,[2][3][4][5] as well as some anticholinergic action,[6][7] and produces both anorectic and pro-sexual effects in animal studies.[8][9]
See also
References
- ↑ "RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane): central effects of a new dopamine receptor agonist". The Journal of Pharmacology and Experimental Therapeutics 224 (1): 161–70. January 1983. PMID 6401334. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=6401334.
- ↑ "Effects of semirigid methoxamine analogs on vascular smooth muscle: studies of methoxy-2-aminotetralin and 2-aminoindane derivatives". Archives Internationales de Pharmacodynamie et de Thérapie 257 (2): 263–73. June 1982. PMID 7114973.
- ↑ "Evidence that a novel dopamine receptor agonist, RDS-127 [2-di-n-propylamino-4,7-dimethoxyindane] has some centrally mediated cardiovascular actions". The Journal of Pharmacy and Pharmacology 36 (5): 318–21. May 1984. doi:10.1111/j.2042-7158.1984.tb04382.x. PMID 6145768.
- ↑ "Failure of pimozide and metergoline to antagonize the RDS-127-induced facilitation of ejaculatory behavior". Physiology & Behavior 37 (1): 47–52. 1986. doi:10.1016/0031-9384(86)90382-3. PMID 3737722.
- ↑ "Evaluation of alpha-adrenoceptor agonistic activity of RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane) in rabbit and rat aortae". Archives Internationales de Pharmacodynamie et de Thérapie 310: 76–86. 1991. PMID 1685313.
- ↑ "The antimuscarinic activity of a dopamine receptor agonist (RDS-127) differentiates M2-muscarinic receptors of heart, ileum and trachea in guinea-pig". Archives Internationales de Pharmacodynamie et de Thérapie 296: 163–72. 1988. PMID 2907277.
- ↑ "Dopamine receptor agonists, N,N-dipropyl-2-aminotetralin (TL-68) and 2-di-n-propylamino-4,7-dimethoxyindane (RDS-127) antagonize oxotremorine-induced tremors by antimuscarinic action in mice". Archives Internationales de Physiologie et de Biochimie 98 (1): 7–9. March 1990. doi:10.3109/13813459009115730. PMID 1692697.
- ↑ "Potent anorexic-like effects of RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane) in the rat: a comparison with other dopamine-receptor agonists". Neuropharmacology 21 (9): 885–90. September 1982. doi:10.1016/0028-3908(82)90080-6. PMID 6897285.
- ↑ "Differential interactions of "prosexual" drugs with 5-hydroxytryptamine1A and alpha 2-adrenergic receptors". Behavioral Neuroscience 100 (5): 664–8. October 1986. doi:10.1037/0735-7044.100.5.664. PMID 2877677.
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