Chemistry:Bimakalim
From HandWiki
| |
| Names | |
|---|---|
| Preferred IUPAC name
2,2-Dimethyl-4-(2-oxopyridin-1(2H)-yl)-2H-1-benzopyran-6-carbonitrile | |
| Identifiers | |
3D model (JSmol)
|
|
| ChEMBL | |
| ChemSpider | |
PubChem CID
|
|
| UNII | |
| |
| |
| Properties | |
| C17H14N2O2 | |
| Molar mass | 278.311 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Bimakalim is a potassium channel opener.[1] It can be prepared from 2-acetyl-4-cyanophenol.[2]
References
- ↑ Puddu, Paolo Emilio; Garlid, Keith D; Monti, Francesco; Iwashiro, Katsunori; Picard, Sandra; Dawodu, Amos Adeyemo; Criniti, Anna; Ruvolo, Giovanni et al. (2006). "Bimakalim: A Promising KATP Channel Activating Agent". Cardiovascular Drug Reviews 18: 25. doi:10.1111/j.1527-3466.2000.tb00031.x.
- ↑ Bergmann, Rolf; Gericke, Rolf (1990). "Synthesis and antihypertensive activity of 4-(1,2-dihydro-2-oxo-1-pyridyl)-2H-1-benzopyrans and related compounds, new potassium channel activators". Journal of Medicinal Chemistry (American Chemical Society (ACS)) 33 (2): 492–504. doi:10.1021/jm00164a005. ISSN 0022-2623.
 |  |
