Chemistry:Pranidipine

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Short description: Antihypertensive drug of the calcium channel blocker class
Pranidipine
Pranidipine structure.svg
Names
Preferred IUPAC name
Methyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Other names
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-methyl O3-[(E)-3-phenylprop-2-enyl] ester
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH C048161
UNII
Properties
C25H24N2O6
Molar mass 448.46786
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Pranidipine is a calcium channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group.[1]

References

  1. Jin Yang; Keisuke Fukuo; Shigeto Morimoto; Tadaaki Niinobu; Toshimitsu Suhara; Toshio Ogihara (2000). "Pranidipine Enhances the Action of Nitric Oxide Released From Endothelial Cells". Hypertension 35 (1 Pt 1): 82–85. doi:10.1161/01.hyp.35.1.82. PMID 10642279. http://hyper.ahajournals.org/content/35/1/82.full.