Chemistry:Niludipine

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Niludipine
Niludipine.svg
Names
Preferred IUPAC name
Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Other names
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid bis(2-propoxyethyl) ester
Identifiers
3D model (JSmol)
ChemSpider
EC Number
  • 245-120-6
MeSH C019497
UNII
Properties
C25H34N2O8
Molar mass 490.553 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Niludipine is a calcium channel blocker of the dihydropyridine class. It is a vasodilator that acts upon the coronary arteries of the heart-lung. It was found to produce a calcium antagonistic effect on the smooth muscle of hearts of canines and guinea pigs inhibiting myocardial oxidative metabolism.[1]

References

  1. Hashimoto, K (1979). "Effects of niludipine on the Cardiovascular system with a note on its Calcium-Antagonistic effects.". Arzneimittel-Forschung 29 (9): 1368–73. PMID 583243.