Chemistry:Bunaftine

Bunaftine
Clinical data
ATC code	C01BD03 (WHO) ;
Identifiers
	IUPAC name N-[2-(Diethylamino)ethyl]-N-propylnaphthalene-1-carboxamide;
CAS Number	32421-46-8 ;
PubChem CID	36131;
ChemSpider	33233 ;
UNII	GH09PRQ3FU;
KEGG	D07428 ;
ChEMBL	ChEMBL2104200;
Chemical and physical data
Formula	C21H30N2O
Molar mass	326.484 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12;
	InChI InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3 ; Key:WWGZXRYELYWJBD-UHFFFAOYSA-N ;
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Short description: Chemical compound

Bunaftine (or bunaphtine^[1]) is an antiarrhythmic agent.^[2] It is classified in class III.^[3]

References

↑ Tamargo J (August 1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther 246 (2): 224–36. PMID 7436628.
↑ "Intropic effects of several antiarrhythmic drugs". Jpn Heart J 24 (3): 377–90. May 1983. doi:10.1536/ihj.24.377. PMID 6876382.
↑ "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J 39 (7): 787–94. July 1977. doi:10.1136/hrt.39.7.787. PMID 328029.

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Clinical data

ATC code	C01BD03 (WHO)
Identifiers
IUPAC name N-[2-(Diethylamino)ethyl]-N-propylnaphthalene-1-carboxamide
CAS Number	32421-46-8^Y
PubChem CID	36131
ChemSpider	33233^Y
UNII	GH09PRQ3FU
KEGG	D07428^Y
ChEMBL	ChEMBL2104200
Chemical and physical data
Formula	C₂₁H₃₀N₂O
Molar mass	326.484 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12
InChI InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3^Y Key:WWGZXRYELYWJBD-UHFFFAOYSA-N^Y
(verify)