Chemistry:Psychotridine

From HandWiki
Short description: Chemical compound
Psychotridine
Psychotridine.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC55H62N10
Molar mass863.171 g·mol−1
3D model (JSmol)

Psychotridine is an alkaloid found in some species of the genus Psychotria, namely Psychotria colorata,[1] but also Psychotria forsteriana,[2] Psychotria lyciiflora,[3] Psychotria oleoides,[3] and Psychotria beccarioides.[4] Psychotridine has analgesic effects and dose-dependently inhibits dizocilpine binding to cortical membranes in vitro, suggesting that it acts as a non-competitive NMDA receptor antagonist.[1]

See also

References

  1. 1.0 1.1 "Involvement of NMDA receptors in the analgesic properties of psychotridine". Phytomedicine 8 (3): 202–206. May 2001. doi:10.1078/0944-7113-00025. PMID 11417913. 
  2. "Polyindolinic Alkaloids from Psychotria forsteriana. Potent Inhibitors of the Aggregation of Human Platelets". Planta Medica 51 (4): 300–303. August 1985. doi:10.1055/s-2007-969496. PMID 17340518. 
  3. 3.0 3.1 "Pyrrolidinoindoline alkaloids from Psychotria oleoides and Psychotria lyciiflora". Journal of Natural Products 62 (6): 838–843. June 1999. doi:10.1021/np9805387. PMID 10395499. 
  4. "Psychotridine, a C55H62N10 alkaloid from Psychotria beccarioides (Rubiaceae)". Australian Journal of Chemistry 27 (3): 639–646. 1974. doi:10.1071/ch9740639.