Biology:CNGB1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.

See also

• Cyclic nucleotide-gated ion channel

Further reading

• "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.". Pharmacol. Rev. 57 (4): 455–62. 2006. doi:10.1124/pr.57.4.8. PMID 16382102. 
• "A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers.". Invest. Ophthalmol. Vis. Sci. 45 (12): 4433–9. 2005. doi:10.1167/iovs.04-0544. PMID 15557452. 
• "Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels.". Proc. Natl. Acad. Sci. U.S.A. 99 (12): 8424–9. 2002. doi:10.1073/pnas.122015999. PMID 12048242. Bibcode: 2002PNAS...99.8424T. 
• "The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes.". J. Biol. Chem. 276 (51): 48009–16. 2002. doi:10.1074/jbc.M108941200. PMID 11641407. 
• "Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.". Hum. Genet. 108 (4): 328–34. 2001. doi:10.1007/s004390100496. PMID 11379879. 
• "Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10.". Mol. Cell. Biol. 20 (23): 9028–40. 2000. doi:10.1128/MCB.20.23.9028-9040.2000. PMID 11074001. 
• "Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors.". Nature 400 (6746): 761–6. 1999. doi:10.1038/23468. PMID 10466724. Bibcode: 1999Natur.400..761K. 
• "The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit.". FEBS Lett. 389 (2): 213–8. 1996. doi:10.1016/0014-5793(96)00588-1. PMID 8766832. 
• "A new subunit of the cyclic nucleotide-gated cation channel in retinal rods.". Nature 362 (6422): 764–7. 1993. doi:10.1038/362764a0. PMID 7682292. Bibcode: 1993Natur.362..764C. 
• "cDNA, gene structure, and chromosomal localization of human GAR1 (CNCG3L), a homolog of the third subunit of bovine photoreceptor cGMP-gated channel.". Genomics 28 (1): 32–8. 1995. doi:10.1006/geno.1995.1102. PMID 7590744. 
• "Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation.". Proc. Natl. Acad. Sci. U.S.A. 91 (24): 11757–61. 1994. doi:10.1073/pnas.91.24.11757. PMID 7526403. Bibcode: 1994PNAS...9111757C. 
• "Stable preparation of aldose reductase isoenzymes from human placenta.". Protein Expr. Purif. 2 (5–6): 420–5. 1992. doi:10.1016/1046-5928(91)90103-P. PMID 1821816. 

External links

• GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview
• CNGB1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Human CNGB1 genome location and CNGB1 gene details page in the UCSC Genome Browser.
• Human GAR1 genome location and GAR1 gene details page in the UCSC Genome Browser.