Biology:KCNT1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Potassium channel subfamily T, member 1, also known as KCNT1 is a human gene that encodes the K_Ca4.1 protein. K_Ca4.1 is a member of the calcium-activated potassium channel protein family

Associated Conditions

Mutations in the KCNT1 gene has been shown to be a cause of Early Infantile Epileptic Encephalopathy.

See also

• SK channel
• Voltage-gated potassium channel

Further reading

• "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. 2000. doi:10.1093/dnares/7.1.65. PMID 10718198. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560. 
• "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. 2004. doi:10.1038/nature02465. PMID 15164053. Bibcode: 2004Natur.429..369H. 
• "International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels.". Pharmacol. Rev. 57 (4): 463–72. 2005. doi:10.1124/pr.57.4.9. PMID 16382103. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.