Biology:KCNG1

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.[1][2][3]

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.[3]

See also

References

  1. "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun 241 (3): 675–81. Feb 1998. doi:10.1006/bbrc.1997.7830. PMID 9434767. 
  2. "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473–508. Dec 2005. doi:10.1124/pr.57.4.10. PMID 16382104. 
  3. 3.0 3.1 "Entrez Gene: KCNG1 potassium voltage-gated channel, subfamily G, member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3755. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.