Biology:KCNG1
 Generic protein structure example |
Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.[1][2][3]
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.[3]
See also
References
- ↑ "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun 241 (3): 675–81. Feb 1998. doi:10.1006/bbrc.1997.7830. PMID 9434767.
- ↑ "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473–508. Dec 2005. doi:10.1124/pr.57.4.10. PMID 16382104.
- ↑ 3.0 3.1 "Entrez Gene: KCNG1 potassium voltage-gated channel, subfamily G, member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3755.
Further reading
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. 2005. doi:10.1038/nbt971. PMID 15146197.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. 2002. doi:10.1038/414865a. PMID 11780052. Bibcode: 2001Natur.414..865D.
- "Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current.". FEBS Lett. 399 (1–2): 177–82. 1997. doi:10.1016/S0014-5793(96)01316-6. PMID 8980147.
External links
- Kv6.1+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
- KCNG1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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