Biology:KCNK10
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Potassium channel, subfamily K, member 10, also known as KCNK10 is a human gene. The protein encoded by this gene, K2P10.1, is a potassium channel containing two pore-forming P domains.[1][2][3]
See also
- Tandem pore domain potassium channel
References
- ↑ "Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors". The Journal of Biological Chemistry 275 (37): 28398–405. September 2000. doi:10.1074/jbc.M002822200. PMID 10880510.
- ↑ "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacological Reviews 57 (4): 527–40. December 2005. doi:10.1124/pr.57.4.12. PMID 16382106. https://escholarship.org/uc/item/3k15p5vt.
- ↑ "K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac". Science 347 (6227): 1256–9. March 2015. doi:10.1126/science.1261512. PMID 25766236.
Further reading
- "Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2". The Journal of Physiology 539 (Pt 3): 657–68. March 2002. doi:10.1113/jphysiol.2001.013432. PMID 11897838.
- "Potassium leak channels and the KCNK family of two-P-domain subunits". Nature Reviews. Neuroscience 2 (3): 175–84. March 2001. doi:10.1038/35058574. PMID 11256078. https://escholarship.org/uc/item/9z7112ns.
- "Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein". British Journal of Pharmacology 154 (8): 1680–90. August 2008. doi:10.1038/bjp.2008.213. PMID 18516069.
- "Large-scale concatenation cDNA sequencing". Genome Research 7 (4): 353–8. April 1997. doi:10.1101/gr.7.4.353. PMID 9110174.
- "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry 236 (1): 107–13. April 1996. doi:10.1006/abio.1996.0138. PMID 8619474.
- "TREK-2, a new member of the mechanosensitive tandem-pore K+ channel family". The Journal of Biological Chemistry 275 (23): 17412–9. June 2000. doi:10.1074/jbc.M000445200. PMID 10747911.
External links
- KCNK10+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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