Biology:TRPM4
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Transient receptor potential cation channel subfamily M member 4 (hTRPM4), also known as melastatin-4, is a protein that in humans is encoded by the TRPM4 gene.[1][2]
TRPM4 Channel Blocker
See also
References
- ↑ "Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform". Proc. Natl. Acad. Sci. U.S.A. 98 (19): 10692–7. September 2001. doi:10.1073/pnas.191360198. PMID 11535825.
- ↑ "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. December 2005. doi:10.1124/pr.57.4.6. PMID 16382100.
Further reading
- Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. 704. Berlin: Springer. pp. 700. ISBN 978-94-007-0264-6.
- "TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization". Cell 109 (3): 397–407. 2002. doi:10.1016/S0092-8674(02)00719-5. PMID 12015988.
- "TRPM4 regulates calcium oscillations after T cell activation". Science 306 (5700): 1374–1377. 2004. doi:10.1126/science.1098845. PMID 15550671.
- "Insights into TRPM4 function, regulation and physiological role". Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology. 179. 2007. pp. 269–85. doi:10.1007/978-3-540-34891-7_16. ISBN 978-3-540-34889-4.
- "Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4". Nat Immunol 8 (3): 312–320. 2007. doi:10.1038/ni1441. PMID 17293867. https://lirias.kuleuven.be/bitstream/123456789/44883/2/Nature+Immunology+Mast+Cell.pdf.
- "The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells". Nat Immunol 9 (10): 1148–56. 2008. doi:10.1038/ni.1648. PMID 18758465.
External links
- TRPM4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Original source: https://en.wikipedia.org/wiki/TRPM4.
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