Biology:KCNK17
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.[1][2]
This gene encodes K2P17.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.[2]
See also
- Tandem pore domain potassium channel
References
- ↑ "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev 57 (4): 527–40. Dec 2005. doi:10.1124/pr.57.4.12. PMID 16382106. https://escholarship.org/uc/item/3k15p5vt.
- ↑ 2.0 2.1 "Entrez Gene: KCNK17 potassium channel, subfamily K, member 17". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=89822.
Further reading
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556.
- "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels". Biochem. Biophys. Res. Commun. 282 (1): 249–56. 2001. doi:10.1006/bbrc.2001.4562. PMID 11263999.
- "Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family". FEBS Lett. 492 (1–2): 84–9. 2001. doi:10.1016/S0014-5793(01)02222-0. PMID 11248242.
External links
- KCNK17+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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