Chemistry:Clofuperol
From HandWiki
Short description: Long acting antipsychotic butyrophenone
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| Other names | Seperidol, R9298 |
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| Formula | C22H22ClF4NO2 |
| Molar mass | 443.87 g·mol−1 |
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Clofluperol is a neuroleptic tranquilizer of the butyrophenone class.[1][2][3] It has the same aromatic piperidinol moiety that is present in penfluridol and fluperamide. The structure can be seen to be a sort of hybrid between that of trifluperidol and haloperidol.
References
- ↑ "[Long-acting neuroleptics. I. Pilot study of clofluperol (R9298)]" (in French). Acta Neurologica et Psychiatrica Belgica 68 (2): 128–136. February 1968. PMID 4972601.
- ↑ "The distribution of the butyrophenones haloperidol, trifluperidol, moperone, and clofluperol in rats, and its relationship with their neuroleptic activity". Arzneimittel-Forschung 19 (2): 199–208. February 1969. PMID 5818759.
- ↑ "Sulman FG: Mammotropic and neuroleptic effects of butyrophenones in the rat". Archives Internationales de Pharmacodynamie et de Therapie 179 (1): 94–105. May 1969. PMID 5388566.
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