Chemistry:2C-F
2C-F, also known as 4-fluoro-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.[1][2] It is taken orally.[1]
Use effects
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists the dose of 2C-F as greater than 250 mg orally and its duration as unknown.[1] At a dose of 250 mg, 2C-F produces slight and uncertain effects including possible modest closed-eye visuals and pleasant lethargy.[1]
Interactions
Pharmacology
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.[1][3]
Chemistry
Properties
2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.
Synthesis
The chemical synthesis of 2C-F has been described.[1]
Analogues
Analogues of 2C-F include 2C-B, 2C-I, 2C-C, DOF, and 25F-NBOMe, among others.[1]
History
2C-F was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1]
Society and culture
Legal status
Canada
As of October 31, 2016, 2C-F is a controlled substance (Schedule III) in Canada.[4]
United States
2C-F is not an explicitly controlled substance in the United States.[5] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. http://www.erowid.org/library/books_online/pihkal/pihkal.shtml. 2C-F Entry in PiHKAL
- ↑ The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. 1. Berkeley: Transform Press. 2011. ISBN 978-0-9630096-3-0.
- ↑ "Structure-activity Relation of Halogenated 2,5-Dimethoxyamphetamines Compared to their α‑Desmethyl (2C) Analogues". The FASEB Journal 36 (S1). 2022. doi:10.1096/fasebj.2022.36.S1.R2121. ISSN 0892-6638. https://www.researchgate.net/publication/360423277_Structure-activity_relation_of_halogenated_25-dimethoxyamphetamines_compared_to_their_a-desmethyl_2C_analogues.
- ↑ "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Controlled Drugs and Substances Act (Government of Canada) 150 (9). 4 May 2016. http://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors72-eng.php.
- ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026, https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf
External links
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