Chemistry:2C-T-3

From HandWiki

2C-T-3, also initially numbered as 2C-T-20 and also known as 4-methallylthio-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-16. It was named by Alexander Shulgin but was never made or tested by him, and was instead first synthesised by Daniel Trachsel some years later. It has a binding affinity of 11nM at 5-HT2A and 40nM at 5-HT2C. It is reportedly a potent psychedelic drug with an active dose in the 15–40 mg range, and a duration of action of 8–14 hours, with visual effects comparable to related drugs such as methallylescaline.[1][2][3] 2C-T-3 is a controlled substance in Canada under phenethylamine blanket-ban language.[4]

See also

References

  1. "Synthesis of novel (phenylalkyl)amines for the investigation of structure-activity relationships. Part 2. 4-Thio-substituted [2-(2,5-dimethoxyphenyl)ethyl]amines (=2,5-dimethoxybenzeneethanamines)". Helvetica Chimica Acta 86 (7): 2610–2619. 2003. doi:10.1002/hlca.200390210. 
  2. "Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs)". Neuropharmacology 134 (Pt A): 141–148. May 2018. doi:10.1016/j.neuropharm.2017.07.012. PMID 28720478. https://edoc.unibas.ch/57358/1/20170920150712_59c2680084ec5.pdf. 
  3. Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. 2013. pp. 788–794. ISBN 978-3-03788-700-4. 
  4. "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html.