Chemistry:Methamnetamine

From HandWiki
Short description: Chemical compound
Methamnetamine
Methamnetamine.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H17N
Molar mass199.297 g·mol−1
3D model (JSmol)

Methamnetamine (also known as methylnaphetamine, MNA, MNT and PAL-1046) is a triple monoamine releasing agent and N-methyl analog of the non-neurotoxic experimental drug naphthylaminopropane and the naphthalene analog of methamphetamine.[1][2][3] It has been sold online as a designer drug.[4][5]

It acts as a releasing agent of serotonin, norepinephrine, and dopamine, with EC50 values of 13 nM, 34 nM, and 10 nM, respectively.[1]

Legal status

Methamnetamine is illegal in Japan.[6]

See also

References

  1. 1.0 1.1 "Studies of the biogenic amine transporters. 14. Identification of low-efficacy "partial" substrates for the biogenic amine transporters". The Journal of Pharmacology and Experimental Therapeutics 341 (1): 251–262. April 2012. doi:10.1124/jpet.111.188946. PMID 22271821. 
  2. "Assessment of the abuse potential of methamnetamine in rodents: a behavioral pharmacology study". Psychopharmacology 238 (8): 2155–2165. August 2021. doi:10.1007/s00213-021-05840-9. PMID 33811503. 
  3. "Characterization of in vitro phase I metabolites of methamnetamine in human liver microsomes by liquid chromatography-quadrupole time-of-flight mass spectrometry". International Journal of Legal Medicine 135 (4): 1471–1476. July 2021. doi:10.1007/s00414-021-02594-z. PMID 33928430. 
  4. "Methamnetamine". WEDINOS. https://www.wedinos.org/db/materials/view/00704. 
  5. "Methamnetamine". New Synthetic Drugs Database. http://nsddb.eu/substance/509/. 
  6. "指定薬物名称・構造式一覧(平成27年9月16日現在)" (in Japanese). 厚生労働省. 16 September 2015. https://www.mhlw.go.jp/seisakunitsuite/bunya/kenkou_iryou/iyakuhin/yakubuturanyou/dl/meisho.pdf.