Chemistry:Morforex

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Short description: Non-marketed appetite suppressant drug
Morforex
Morforex.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC15H24N2O
Molar mass248.370 g·mol−1
3D model (JSmol)

Morforex (INN; Bo 637), also referable to as N-morpholinoethylamphetamine, is an anorectic which was never marketed.[1][2]

It produces amphetamine as an active metabolite.[3]

Synthesis

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Patent:[4]

Amphetamine is reacted with N-Chloroethylmorpholine [3240-94-6] in the presence of IPA solvent.

See also

References

  1. Dictionary of Pharmacological Agents. CRC Press. 21 November 1996. pp. 1377–. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC&pg=PA1377. 
  2. World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0. https://books.google.com/books?id=HcogPwAACAAJ. 
  3. Handbook of Biotransformations of Aromatic Compounds. CRC Press. 10 November 2004. pp. 13–. ISBN 978-0-203-64196-5. https://books.google.com/books?id=luttauRomC8C&pg=SL13-PA98. 
  4. "N-morpholino-1 n-phénylisopropylamino-2 éthane [N-morpholino-1 N-phenylisopropylamino-2 ethane]" FR patent 2199M, published 1963-12-09, assigned to Brevets Pharmaceutiques et Cosmetologiques