Chemistry:Fencamine
Fencamine, also known as methamphetaminoethylcaffeine, is a psychostimulant drug of the amphetamine class. It is closely related to fenethylline.[1] It is metabolized to methamphetamine and amphetamine.[2] The drug also contains a caffeine moiety in its chemical structure.
Fencamine has been experimentally used in the treatment of depression.[2] A clinical report on its use in prolonged reactive depression, an older psychiatric term referring to depressive conditions attributed to psychological stressors, was published in 1970.[3]
A 1974 study described a method for determining fencamine in rat and human urine.[4] According to a 2000 review summarizing the human results, approximately 32% of a 50 mg dose was excreted unchanged in urine within 48 hours.[2]
Names
The National Center for Advancing Translational Sciences Inxight Drugs database lists Altimina and Sicoclor as names for fencamine hydrochloride.[5]
Yet the United Nations Office on Drugs and Crime's Multilingual Dictionary of Narcotic Drugs and Psychotropic Substances lists these names under fencamfamin.[6]
Sicoclor was a registered medicinal product in Argentina until 2011.[7]
See also
References
- ↑ "Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results". Journal of Occupational and Environmental Medicine 44 (5): 435–50. May 2002. doi:10.1097/00043764-200205000-00012. PMID 12024689.
- ↑ 2.0 2.1 2.2 "Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine". Drug Metab Rev 32 (1): 15–44. February 2000. doi:10.1081/dmr-100100562. PMID 10711406. https://isomerdesign.com/bitnest/external/10.1081/DMR-100100562.
- ↑ Quirós e Isla, P. G. (15 December 1970). "Acción del derivado etilendiamínico, fencamina, sobre depresiones reactivas prolongadas" (in es). Revista Clínica Española 119 (5): 437–438. PMID 5505078.
- ↑ "Determination of dl-fencamine in rat and human urine". Arzneimittelforschung 24 (9): 1301–1304. September 1974. PMID 4154765.
- ↑ "Fencamine hydrochloride". National Center for Advancing Translational Sciences. https://drugs.ncats.io/substance/E66PP612U7.
- ↑ United Nations Office on Drugs and Crime. "Part One". Multilingual Dictionary of Narcotic Drugs and Psychotropic Substances. p. 129. https://www.unodc.org/documents/scientific/-%20Part%20One%20ALL.pdf.
- ↑ "Disposición 3520/2011" (in es) (PDF). Administración Nacional de Medicamentos, Alimentos y Tecnología Médica. 17 May 2011. p. 4. https://boletin.anmat.gob.ar/mayo_2011/Dispo_3520-11.pdf.
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