Chemistry:3,4-Dimethylmethcathinone
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| Formula | C12H17NO |
| Molar mass | 191.274 g·mol−1 |
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3,4-Dimethylmethcathinone (3,4-DMMC) is a stimulant drug first reported in 2010 as a designer drug analogue of mephedrone, apparently produced in response to the banning of mephedrone, following its widespread abuse in many countries in Europe and around the world.[1] 3,4-DMMC has been seized as a designer drug in Australia .[2] In vitro, 3,4-DMMC was shown to be a monoamine transporter substrate that potently inhibits norepinephrine and serotonin reuptake, and to a lesser extent dopamine reuptake.[3]
Legal Status
As of October 2015 3,4-DMMC is a controlled substance in China.[4]
3,4-DMMC is banned in the Czech Republic.[5]
In the United States 3,4-DMMC is considered a Schedule I controlled substance as a positional isomer of 4-Methylethcathinone (4-MEC).[6]
See also
- Serotonin–norepinephrine–dopamine reuptake inhibitor
- Serotonin–norepinephrine reuptake inhibitor
- Substituted cathinone
- Indanylaminopropane
- Methylone
- Xylopropamine
References
- ↑ "EMCDDA Annual Report 2010". http://www.emcdda.europa.eu/attachements.cfm/att_132857_EN_EMCDDA-Europol%20Annual%20Report%202010A.pdf.
- ↑ "The characterization of 3,4-dimethylmethcathinone (3,4-DMMC)". Journal of Forensic Sciences 57 (5): 1303–6. September 2012. doi:10.1111/j.1556-4029.2012.02142.x. PMID 22564211.
- ↑ "Pharmacological profile of mephedrone analogs and related new psychoactive substances". Neuropharmacology 15 (134): 4–12. 2018. doi:10.1016/j.neuropharm.2017.07.026. PMID 28755886. https://edoc.unibas.ch/57357/1/20170920120908_59c23e44b5f0e.pdf.
- ↑ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in zh). China Food and Drug Administration. 27 September 2015. http://www.sfda.gov.cn/WS01/CL0056/130753.html.
- ↑ "Látky, o které byl doplněn seznam č. 4 psychotropních látek (příloha č. 4 k nařízení vlády č. 463/2013 Sb.)" (in cs). Ministerstvo zdravotnictví. http://www.mzcr.cz/Admin/_upload/files/3/Nov%C3%A9%20PL.pdf.
- ↑ "Lists of: Scheduling Actions Controlled Substances Regulated Chemicals". U.S. Department of Justice. February 2023. https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf.
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