Medicine:Chloride channel opener
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A chloride channel opener is a type of drug which facilitates ion transmission through chloride channels. An example is 1,10-phenanthroline, which activates Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels.[1]
See also
References
- ↑ Duszyk, Marek; MacVinish, Lesley; Cuthbert, Alan W. (2001). "Phenanthrolines - a new class of CFTR chloride channel openers". British Journal of Pharmacology 134 (4): 853–864. doi:10.1038/sj.bjp.0704328. PMID 11606326.
Further reading
- Cuthbert, Alan W. (2001). "Assessment of CFTR chloride channel openers in intact normal and cystic fibrosis murine epithelia". British Journal of Pharmacology 132 (3): 659–668. doi:10.1038/sj.bjp.0703859. PMID 11159718.
- Ramteke, Vinod D.; Tandan, Surendra K.; Kumar, Dinesh; Aruna Devi, R.; Shukla, Manoj K.; Ravi Prakash, Vellanki (2009). "Increased hyperalgesia by 5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats". Pharmacology Biochemistry and Behavior 91 (3): 417–422. doi:10.1016/j.pbb.2008.08.017. PMID 18775743.
| Types | |
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| Classes | |
| Calcium |
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| Potassium |
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| Sodium |
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| Chloride |
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| Others |
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