Chemistry:2CD-5EtO

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2CD-5EtO, also known as 5-ethoxy-2-methoxy-4-methylphenethylamine, is a psychedelic drug of the phenethylamine, 2C, and TWEETIO families related to 2C-D.[1][2][3] It is the analogue of 2C-D in which the methoxy group at the 5 position has been extended to an ethoxy group.[1][2][3]

Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 2CD-5EtO's dose as 40 to 50 mg orally, its onset as slow and gradual, its time to peak or full effects as about 2 hours, and its duration as 12 hours.[1][2][3] The effects of 2CD-5EtO were said to include being "largely free from excitement", having "a friendly openness and outgoingness that allowed easy talk, interaction, humor", and allowing for healthy appetite.[1]

Interactions

Chemistry

Synthesis

The chemical synthesis of 2CD-5EtO has been described.[1]

History

2CD-5EtO was first described in the literature by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2][4][5][6][7]

Society and culture

2CD-5EtO is a controlled substance in Canada under phenethylamine blanket-ban language.[8]

See also

  • TWEETIO (psychedelics)
  • Darrell Lemaire
  • Iris (DOM-5ETO)
  • 2CB-2EtO

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. http://www.erowid.org/library/books_online/pihkal/pihkal.shtml.  https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml#:~:text=2CD%2D5ETO
  2. ↑ 2.0 2.1 2.2 2.3 "Basic Pharmacology and Effects". Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. 2003. pp. 67–137. ISBN 978-0-12-433951-4. https://bibliography.maps.org/resources/download/12634. 
  3. ↑ 3.0 3.1 3.2 "Structure-activity relationships of the classic hallucinogens and their analogs". NIDA Research Monograph 146: 74–91. 1994. PMID 8742795. http://www.erowid.org/psychoactives/journals/psychoactives_journal8.shtml. 
  4. ↑ "Erowid Darrell Lemaire Vault". https://erowid.org/culture/characters/lemaire_darrell/lemaire_darrell.shtml. 
  5. ↑ Morris H (7 December 2016). "The Lazy Lizard School of Hedonism". Hamilton's Pharmacopeia. Season 1. Episode 6. Vice Media. Viceland.
  6. ↑ "Notes About Psychoactive Compounds". Radiant Minds: Scientists Explore the Dimensions of Consciousness. Millay. 2010. pp. 201–207. ISBN 978-0-615-29633-3. https://erowid.org/culture/characters/lemaire_darrell/lemaire_darrell_article1.pdf. 
  7. ↑ Lazar (Darrell Lemaire); Hosteen Nez (1990). Certain Exotic Transmitters as Smart Pills or Compounds that Increase the Capacity for Mental Work in Humans: A Story About LAZAR as Told by Hosteen Nez (2nd ed.). https://erowid.org/chemicals/2cd/2cd_smartpills1.pdf. 
  8. ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 



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