Chemistry:Atamestane
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Short description: Chemical compound
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| Other names | SH-489; Metandroden; 1-Methylandrosta-1,4-diene-3,17-dione |
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| Formula | C20H26O2 |
| Molar mass | 298.426 g·mol−1 |
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Atamestane (developmental code name SH-489), also known as metandroden, as well as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer.[1] It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.[2][additional citation(s) needed]
See also
- Boldione (androsta-1,4-diene-3,17-dione)
References
- ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 794–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA794.
- ↑ "Atamestane: an aromatase inhibitor for the treatment of benign prostatic hyperplasia. A short review". The Journal of Steroid Biochemistry and Molecular Biology 44 (4–6): 565–72. March 1993. doi:10.1016/0960-0760(93)90260-4. PMID 7682838.
External links
- Atamestane entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
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