Chemistry:Penmesterol
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Short description: Chemical compound
Clinical data | |
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Trade names | Pandocrine; Testopan |
Other names | RP-12222; 17α-Methyltestosterone 3-cyclopentyl enol ether |
Routes of administration | By mouth |
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Chemical and physical data | |
Formula | C25H38O2 |
Molar mass | 370.577 g·mol−1 |
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Penmesterol (INN) (brand names Pandrocine, Testopan; former developmental code name RP-12222), or penmestrol, also known as 17α-methyltestosterone 3-cyclopentyl enol ether,[1] is a synthetic, orally active anabolic-androgenic steroid (AAS) that was developed in the early 1960s.[2][3][4][5] It is the 3-cyclopentyl enol ether of methyltestosterone.[6][7]
See also
References
- ↑ Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. 4 October 2001. p. 2653. ISBN 978-3-527-30247-5. https://books.google.com/books?id=1XBqAAAAMAAJ.
- ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 942–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA942.
- ↑ Azziz, Ricardo (8 November 2007). Androgen Excess Disorders in Women. Springer Science & Business Media. pp. 122–. ISBN 978-1-59745-179-6. https://books.google.com/books?id=Ch-BsGAOtucC&pg=PA122.
- ↑ Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. 22 October 2013. pp. 2935–. ISBN 978-0-8155-1856-3. https://books.google.com/books?id=_J2ti4EkYpkC&pg=PA2935-IA233.
- ↑ Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. 12 March 2013. pp. 504–. ISBN 978-3-642-65035-2. https://books.google.com/books?id=4TWnBgAAQBAJ&pg=PA504.
- ↑ "Δ4-3-Keto Steroidal Enol Ethers. Paradoxical Dependency of Their Effectiveness on the Administration Route". Journal of the American Chemical Society 82 (3): 746–748. 1960. doi:10.1021/ja01488a062.
- ↑ The Practice of Medicinal Chemistry. Academic Press. 2 May 2011. pp. 731–. ISBN 978-0-08-056877-5. https://books.google.com/books?id=Qmt1_DQkCpEC&pg=PA731.
{{Navbox
| name = Androgens and antiandrogens | title = Androgens and antiandrogens | state = collapsed | listclass = hlist | groupstyle = text-align:center;
| group1 = Androgens
(incl. AAS)
| list1 =
| group2 = Antiandrogens | list2 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 9em;
| group1 = AR antagonists | list1 =
- Steroidal: Abiraterone acetate
- Canrenone
- Chlormadinone acetate
- Cyproterone acetate
- Delmadinone acetate
- Dienogest
- Drospirenone
- Medrogestone
- Megestrol acetate
- Nomegestrol acetate
- Osaterone acetate
- Oxendolone
- Potassium canrenoate
- Spironolactone
- Nonsteroidal: Apalutamide
- Bicalutamide
- Cimetidine
- Darolutamide
- Enzalutamide
- Flutamide
- Ketoconazole
- Nilutamide
- Seviteronel†
- Topilutamide (fluridil)
| group2 = Steroidogenesis| list2 =
inhibitors
5α-Reductase | |
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Others |
| group3 = Antigonadotropins | list3 =
- D2 receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (e.g., bifluranol, [[diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
- GnRH agonists (e.g., leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Progestogens (incl., chlormadinone acetate, [[cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, [[Chemistry:Medroxyprogesterone medroxyprogesterone acetate, Chemistry:Megestrol acetate|megestrol acetate]])
| group4 = Others | list4 =
- Androstenedione immunogens: Androvax (androstenedione albumin)
- Ovandrotone albumin (Fecundin)
}}
| liststyle = background:#DDDDFF;| list3 =
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Androgen receptor modulators
- Estrogens and antiestrogens
- Progestogens and antiprogestogens
- List of androgens/anabolic steroids
}}
Original source: https://en.wikipedia.org/wiki/Penmesterol.
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