Chemistry:Delanterone
From HandWiki
Short description: Chemical compound
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| Other names | GBR-21162; 1α-Methylandrosta-4,16-dien-3-one |
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| Formula | C20H28O |
| Molar mass | 284.443 g·mol−1 |
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Delanterone (INN) (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed.[1][2][3] The compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short terminal half-life, and likely in relation to this was not further developed.[3] It was described and characterized in the literature in 1977.[1][3]
See also
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 794–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA794.
- ↑ Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. 2001. ISBN 978-3-527-30247-5. https://books.google.com/books?id=zmpqAAAAMAAJ.
- ↑ 3.0 3.1 3.2 "Androgen receptor antagonists (antiandrogens): structure-activity relationships". Current Medicinal Chemistry 7 (2): 211–47. February 2000. doi:10.2174/0929867003375371. PMID 10637363.
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