Chemistry:Bolazine capronate

Short description: Chemical compound

Bolazine capronate

Clinical data
Trade names	Roxilon Inject
Other names	Bolazine caproate; Bolazine hexanoate; Di(drostanolone capronate) azine; 2α-Methyl-5α-androstan-17β-ol-3-one 17β-hexanoate azine
Routes of administration	Intramuscular injection
Identifiers
IUPAC name (1S,2S,4R,5Z,7S,10R,11S,14S,15S)-5-{2-[(1S,2S,4R,5E,7S,10R,11S,14S,15S)-14-(hexanoyloxy)-2,4,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-ylidene]hydrazin-1-ylidene}-2,4,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl hexanoate
ChemSpider	8254591
Chemical and physical data
Formula	C52H84N2O4
Molar mass	801.254 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C\C(=N\N=C5/C[C@@H]6CC[C@H]7[C@@H]8CC[C@H](OC(=O)CCCCC)[C@@]8(C)CC[C@@H]7[C@@]6(C)C[C@H]5C)[C@H](C)C[C@]4(C)[C@H]3CC[C@]12C
InChI InChI=1S/C52H84N2O4/c1-9-11-13-15-47(55)57-45-23-21-39-37-19-17-35-29-43(33(3)31-51(35,7)41(37)25-27-49(39,45)5)53-54-44-30-36-18-20-38-40-22-24-46(58-48(56)16-14-12-10-2)50(40,6)28-26-42(38)52(36,8)32-34(44)4/h33-42,45-46H,9-32H2,1-8H3/b53-43-,54-44+/t33-,34-,35+,36+,37+,38+,39+,40+,41+,42+,45+,46+,49?,50+,51?,52+/m1/s1 Key:AOAFJVPZPNBTQX-VNBRUOELSA-N

Bolazine capronate (INN) (brand name Roxilon Inject), also known as bolazine caproate or bolazine hexanoate, as well as di(drostanolone capronate) azine or 2α-methyl-5α-androstan-17β-ol-3-one 17β-hexanoate azine, is a synthetic, injected androgen/anabolic steroid (AAS), and derivative of dihydrotestosterone (DHT). It is an androgen ester – specifically, the C17β hexanoate ester of bolazine.

See also

• List of androgen esters § Dihydrotestosterone esters

References

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| name = Androgens and antiandrogens
| title = Androgens and antiandrogens
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| group1 = Androgens
(incl. AAS)

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AR agonists

Testosterone derivatives: Androstenediol dipropionate Boldenone undecylenate Clostebol Clostebol acetate Clostebol caproate Clostebol propionate Cloxotestosterone acetate Prasterone (dehydroepiandrosterone, DHEA) Prasterone enanthate (DHEA enanthate) Prasterone sulfate (DHEA sulfate) Quinbolone Testosterone# Testosterone esters (e.g., testosterone cypionate, testosterone enanthate]], testosterone propionate]], testosterone undecanoate]], testosterone ester mixture]]s (Deposterona, Omnadren, Sustanon, Testoviron Depot)) Dihydrotestosterone derivatives: Androstanolone (stanolone, dihydrotestosterone, DHT) Androstanolone esters Bolazine capronate Drostanolone propionate (dromostanolone propionate) Epitiostanol Mepitiostane Mesterolone Metenolone acetate (methenolone acetate) Metenolone enanthate (methenolone enanthate) Stenbolone acetate 19-Nortestosterone derivatives: Bolandiol dipropionate Nandrolone esters (e.g., nandrolone decanoate, nandrolone phenylpropionate) Norclostebol Norclostebol acetate Oxabolone cipionate (oxabolone cypionate) Trenbolone acetate Trenbolone hexahydrobenzylcarbonate (trenbolone cyclohexylmethylcarbonate) 17α-Alkylated testosterone derivatives: Bolasterone Calusterone Chlorodehydromethyltestosterone (CDMT) Fluoxymesterone Formebolone Metandienone (methandienone, methandrostenolone) Methandriol (methylandrostenediol) Methandriol bisenanthoyl acetate Methandriol dipropionate Methandriol propionate Methyltestosterone Methyltestosterone 3-hexyl ether Oxymesterone Penmesterol Tiomesterone (thiomesterone) 17α-Alkylated dihydrotestosterone derivatives: Androisoxazole Furazabol Mebolazine (dimethazine) Mestanolone Oxandrolone Oxymetholone Stanozolol 17α-Alkylated 19-nortestosterone derivatives: Ethylestrenol Mibolerone Norethandrolone Normethandrone (methylestrenolone, normethisterone) Propetandrol (propethandrol) 17α-Vinyltestosterone derivatives: Norvinisterone (vinylnortestosterone) 17α-Ethynyltestosterone derivatives: Danazol Gestrinone Progestins (e.g., ethisterone (ethynyltestosterone), levonorgestrel, norgestrel, norethisterone (norethindrone), [[Chemistry:Lynestrlynestrenol, Norgestrienone|norgestrienone]]) Tibolone Progesterone derivatives: Medroxyprogesterone acetate

Progonadotropins

Antiestrogens (e.g., tamoxifen, Chemistry:Clomifene

| group2 = Antiandrogens
| list2 = {{Navbox|child
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  | group1 = AR antagonists
  | list1 =

• Steroidal: Abiraterone acetate
• Canrenone
• Chlormadinone acetate
• Cyproterone acetate
• Delmadinone acetate
• Dienogest
• Drospirenone
• Medrogestone
• Megestrol acetate
• Nomegestrol acetate
• Osaterone acetate
• Oxendolone
• Potassium canrenoate
• Spironolactone

• Nonsteroidal: Apalutamide
• Bicalutamide
• Cimetidine
• Darolutamide
• Enzalutamide
• Flutamide
• Ketoconazole
• Nilutamide
• Seviteronel^†
• Topilutamide (fluridil)

  | group2 = Steroidogenesis
inhibitors

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5α-Reductase	Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract
Others	Abiraterone acetate Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel† Spironolactone

  | group3 = Antigonadotropins
  | list3 =

• D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
• Estrogens (e.g., bifluranol, [[diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
• GnRH agonists (e.g., leuprorelin)
• GnRH antagonists (e.g., cetrorelix)
• Progestogens (incl., chlormadinone acetate, [[cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, [[Chemistry:Medroxyprogesterone medroxyprogesterone acetate, Chemistry:Megestrol acetate|megestrol acetate]])

  | group4 = Others
  | list4 =

• Androstenedione immunogens: Androvax (androstenedione albumin)
• Ovandrotone albumin (Fecundin)

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• ^#WHO-EM
• ^‡Withdrawn from market
• Clinical trials:
  • ^†Phase III
  • ^§Never to phase III

See also

Androgen receptor modulators

Estrogens and antiestrogens

Progestogens and antiprogestogens

List of androgens/anabolic steroids

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