Chemistry:Meta-DOB
Meta-DOB, also known as 5-bromo-2,4-dimethoxyamphetamine, is a psychoactive drug of the phenethylamine and amphetamine families related to the psychedelic drug DOB.[1] It is a positional isomer of DOB in which the bromine atom at the 4 position and the methoxy group at the 5 position have been interchanged.[1]
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists meta-DOB's dose range as 50 to 100 mg orally and its duration as 5 to 6 hours.[1] The effects of meta-DOB have been reported to include MDA-like effects, vague uneasiness, possible threshold psychedelic effects, anxiety, paranoid fantasies, and toxic signs such as flushing, palpitations, and occasional nausea, vomiting, and diarrhea.[1][2] It has been said that any possible psychedelic effects of meta-DOB seem to have been blurred by its more obvious toxic effects.[1]
The chemical synthesis of meta-DOB has been described.[1] A notable analogue of meta-DOB is meta-DOT.[1]
Meta-DOB was first described in the scientific literature by Silvia Sepúlveda and colleagues by 1972.[2] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]
See also
- Substituted methoxyphenethylamine
- DOx § Related compounds
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. http://www.erowid.org/library/books_online/pihkal/pihkal.shtml.
- ↑ 2.0 2.1 "Potential psychotomimetics. New bromoalkoxyamphetamines". J Med Chem 15 (4): 413–415. April 1972. doi:10.1021/jm00274a022. PMID 5019563.
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