Chemistry:5α-Androst-2-ene-17-one

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Short description: Chemical compound
5α-Androst-2-ene-17-one
5alpha-androst-2-ene-17-one.svg
Clinical data
Other names5α-Androst-2-en-17-one; 17-Oxo-5α-androst-2-ene; Delta-2-androst-17-one; (+)-Androst-2-en-17-one; Occlesterone
Routes of
administration
Oral
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC19H28O
Molar mass272.432 g·mol−1
3D model (JSmol)

5α-Androst-2-en-17-one is an endogenous, naturally occurring, orally active anabolic-androgenic steroid (AAS) and a derivative of dihydrotestosterone (DHT). It is a metabolite of dehydroepiandrosterone (DHEA) in the body[1][2] and is also a pheromone found in elephants and boars.[3] 5α-Androst-2-en-17-one has been sold on the Internet as a "dietary supplement". It resembles desoxymethyltestosterone (17α-methyl-5α-androst-2-en-17β-ol) in chemical structure and may act as an androgen prohormone.

References

  1. "Influence of oral dehydroepiandrosterone (DHEA) on urinary steroid metabolites in males and females". Steroids 65 (2): 98–102. February 2000. doi:10.1016/S0039-128X(99)00090-2. PMID 10639021. 
  2. "Transformations of steroid sulphates by human axillary bacteria. A mechanism for human odour formation?". Biochemical Society Transactions 25 (1): 16S. February 1997. doi:10.1042/bst025016s. PMID 9056914. 
  3. Chemical signals in vertebrates 9. 9. Springer. 2001. pp. 131. ISBN 978-0-306-46682-3.