Chemistry:2T-MMDA-3a

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2T-MMDA-3a, also known as 2-methylthio-3,4-methylenedioxyamphetamine (2-MeS-MDA), is a psychedelic drug of the phenethylamine, amphetamine, and MDxx families related to 3,4-methylenedioxyamphetamine (MDA).[1][2] It is the derivative of MDA with a 2-methylthio substitution and is the analogue of MMDA-3a with a 2-methylthio group instead of a 2-methoxy group.[1][2]

2T-MMDA-3a was included as an entry in Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved).[1][2] Its dose was listed as greater than 12 mg orally, its duration was listed as unknown, and its effects were not described.[1][3][2] However, in Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds, he stated that a 12 mg dose produced threshold effects, but he did not assess higher doses.[1][3][2] In addition, Daniel Trachsel has classified 2T-MMDA-3a as a hallucinogen.[1]

The chemical synthesis of 2T-MMDA-3a was described by Shulgin in PiHKAL.[2] Numerous other sulfur-containing phenethylamine analogues are also possible.[2][3][1]

2T-MMDA-3a was first described in the scientific literature by Shulgin in PiHKAL in 1991.[3][2] It is a controlled substance in Canada under phenethylamine blanket-ban language.[4]

See also

  • Substituted methylenedioxyphenethylamine
  • 4T-MMDA-2

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 (in de) Phenethylamine: von der Struktur zur Funktion. Nachtschatten-Science (1 ed.). Solothurn: Nachtschatten-Verlag. 2013. ISBN 978-3-03788-700-4. OCLC 858805226. https://books.google.com/books?id=-Us1kgEACAAJ. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. http://www.erowid.org/library/books_online/pihkal/pihkal.shtml.  "2T-MMDA-3a". https://erowid.org/library/books_online/pihkal/pihkal166.shtml. 
  3. ↑ 3.0 3.1 3.2 3.3 The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. 1. Berkeley: Transform Press. 2011. ISBN 978-0-9630096-3-0. "2T-MMDA-3a [...] (6,7) [...] (6) Synthesis (Shulgin and Shulgin, 1991). (7) Threshold oral activity in humans at 12 mg; duration unknown (Shulgin and Shulgin, 1991)." 
  4. ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 



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