Chemistry:Isomescaline
Isomescaline (IM), also known as 2,3,4-trimethoxyphenethylamine (2,3,4-TMPEA) or as TMPEA-3 or 2C-TMA-3, is a chemical compound related to mescaline (3,4,5-trimethoxyphenethylamine).[1] It is a positional isomer of mescaline, as well as an analogue of TIM-2, TIM-3, and TIM-4.[1] In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists its dose as greater than 400 mg orally and its duration as unknown.[1] Despite its structural similarity to mescaline, isomescaline produced no effects in humans.[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of isomescaline.[1] Isomescaline was first described in the scientific literature by Clark and colleagues by 1965.[2] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1] Isomescaline is not a controlled substance in Canada as of 2025.[3]
See also
- Trimethoxyphenethylamine
- Substituted methoxyphenethylamine
- Scaline
- 2,3,4-Trimethoxyamphetamine (2,3,4-TMA; TMA-3)
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 "Erowid Online Books : "PIHKAL" - #91 IM". https://www.erowid.org/library/books_online/pihkal/pihkal091.shtml.
- ↑ "The Effects of Ring-Methoxyl Groups on Biological Deamination of Phenethylamines". J Med Chem 8 (3): 353–355. May 1965. doi:10.1021/jm00327a016. PMID 14323146.
- ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html.
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