Chemistry:18-Methyltestosterone

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Short description: Chemical compound
18-Methyltestosterone
18-Methyltestosterone.svg
Clinical data
Other names18-MT; 18-Methylandrost-4-en-17β-ol-3-one; 13β-Ethyl-17β-hydroxy-18-norandrost-4-en-3-one
Drug classAndrogen; Anabolic steroid
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC20H30O2
Molar mass302.458 g·mol−1
3D model (JSmol)

18-Methyltestosterone (18-MT) is an androgen/anabolic steroid (AAS) which was never marketed.[1][2][3] Along with 19-nortestosterone (nandrolone) and 17α-ethynyltestosterone (ethisterone), it is a parent structure of a number of progestogens and AAS. These include the progestogens levonorgestrel (17α-ethynyl-18-methyl-19-nortestosterone) and its derivatives (e.g., desogestrel, gestodene, norgestimate, gestrinone) as well as AAS such as norboletone (17α-ethyl-18-methyl-19-nortestosterone) and tetrahydrogestrinone (THG; δ9,11-17α-ethyl-18-methyl-19-nortestosterone).

See also

  • List of androgens/anabolic steroids

References

  1. "Steroids. CCLXXXVIII.1The Synthesis of 18-Methylprogesterone and Related Compounds2". The Journal of Organic Chemistry 31 (4): 1026–1032. 1966. doi:10.1021/jo01342a009. ISSN 0022-3263. 
  2. "Totally Synthetic Hormones. XVI.(1) The Conversion of Estr-4-en-17-ol to Testosterone and the Total Synthesis of Some 18-Methylandrostane and 18-Methylpregnane Derivatives". Journal of Medicinal Chemistry 10 (3): 446–451. May 1967. doi:10.1021/jm00315a034. PMID 22185150. 
  3. "Totally synthetic steroid hormones. XVII. Further studies on the synthesis of dl-18-methylandrostane and dl-18-methylpregnane derivatives". Journal of Medicinal Chemistry 10 (5): 783–789. September 1967. doi:10.1021/jm00317a006. PMID 6048483.