Chemistry:2C-I-FLY

From HandWiki

2C-I-FLY is a psychedelic drug of the phenethylamine, 2C, and FLY families.[1][2] It is the FLY (benzodifuran) derivative of 2C-I and an analogue of 2C-B-FLY.[1][2] The monoamine oxidase (MAO) interactions of 2C-I-FLY have been described.[2] 2C-I-FLY produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.[1] It showed about 3-fold lower potency than 2C-B-FLY and 2C-E-FLY in this assay, but was only slightly less potent than 2C-EF-FLY.[1] 2C-I-FLY was first described in the scientific literature by Lea Wagmann and colleagues in 2018 or 2019.[3][1][2]

See also

  • FLY (psychedelics)

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 "Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs". Neuropharmacology 144: 368–376. January 2019. doi:10.1016/j.neuropharm.2018.10.037. PMID 30385253. 
  2. ↑ 2.0 2.1 2.2 2.3 "Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases". Drug Testing and Analysis 11 (2): 318–324. February 2019. doi:10.1002/dta.2494. PMID 30188017. 
  3. ↑ Wagmann L (2018). Psychoactive substances as substrates or inhibitors of enzymes in drug metabolism and transport (Ph.D. thesis). Universität Des Saarlandes. doi:10.22028/D291-27544. Retrieved 12 March 2026.



Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:2C-I-FLY&oldid=4308656"