Chemistry:Epithelial sodium channel blocker
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An epithelial sodium channel blocker is a sodium channel blocker that is selective for the epithelial sodium channel.
An example is amiloride, which is used in the treatment of hypertension.[1]
References
- ↑ Sagnella GA, Swift PA (2006). "The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure". Curr. Pharm. Des. 12 (18): 2221–34. doi:10.2174/138161206777585157. PMID 16787251. http://www.bentham-direct.org/pages/content.php?CPD/2006/00000012/00000018/0004B.SGM.
Sulfonamides (and etacrynic acid) |
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Potassium-sparing (at CD) |
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Osmotic diuretics (PT, DL) | |||||||||
Vasopressin receptor inhibitors (DCT and CD) | |||||||||
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