Chemistry:7-Spiroindanyloxymorphone
From HandWiki
Short description: Chemical compound
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| Formula | C25H25NO4 |
| Molar mass | 403.478 g·mol−1 |
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7-Spiroindanyloxymorphone (SIOM) is a drug that is used in scientific research. It is a selective δ-opioid agonist. It is a derivative of oxymorphone.[1][2][3][4][5]
References
- ↑ "A selective delta 1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists". Journal of Medicinal Chemistry 36 (17): 2572–4. August 1993. doi:10.1021/jm00069a017. PMID 8394935.
- ↑ "7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands". Journal of Medicinal Chemistry 40 (19): 3064–70. September 1997. doi:10.1021/jm970283e. PMID 9301669.
- ↑ "7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors". Journal of Medicinal Chemistry 40 (11): 1720–5. May 1997. doi:10.1021/jm9700880. PMID 9171881.
- ↑ "14-Desoxy analogues of naltrindole and 7-spiroindanyloxymorphone: the role of the 14-hydroxy group at delta opioid receptors". Journal of Medicinal Chemistry 41 (14): 2657–60. July 1998. doi:10.1021/jm980209b. PMID 9651172.
- ↑ "A three-dimensional model of the delta-opioid pharmacophore: comparative molecular modeling of peptide and nonpeptide ligands". Biopolymers 53 (7): 565–80. June 2000. doi:10.1002/(SICI)1097-0282(200006)53:7<565::AID-BIP4>3.0.CO;2-5. PMID 10766952.
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