Chemistry:Ciclopramine

Ciclopramine
Clinical data
ATC code	None;
Legal status
Legal status	Not marketed;
Identifiers
	IUPAC name N-Methyl-2,3,7,8-tetrahydro-1H-quino[1,8-ab][1]benzazepin-3-amine;
CAS Number	33545-56-1;
PubChem CID	160410;
ChemSpider	140965;
UNII	BXS8X8APGS;
ChEMBL	ChEMBL2105933;
Chemical and physical data
Formula	C18H20N2
Molar mass	264.372 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c14c2c(ccc1)C(NC)CCN2c3ccccc3CC4;

Short description: Tetracyclic antidepressant

Ciclopramine is a tetracyclic antidepressant (TeCA) that was never marketed.^[1]^[2]

References

↑ Dictionary of pharmacological agents. London: Chapman & Hall. 1997. ISBN 9780412466304. OCLC 223303192. https://books.google.com/books?id=A0THacd46ZsC.
↑ "Pharmaco-EEG profiles of typical and atypical antidepressants". Advances in Biochemical Psychopharmacology 32: 257–268. 1982. PMID 7090895. https://pubmed.ncbi.nlm.nih.gov/7090895/.

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Original source: https://en.wikipedia.org/wiki/Ciclopramine. Read more

[Triggle1997-1] Dictionary of pharmacological agents. London: Chapman & Hall. 1997. ISBN 9780412466304. OCLC 223303192. https://books.google.com/books?id=A0THacd46ZsC.

[Saletu1982-2] "Pharmaco-EEG profiles of typical and atypical antidepressants". Advances in Biochemical Psychopharmacology 32: 257–268. 1982. PMID 7090895. https://pubmed.ncbi.nlm.nih.gov/7090895/.

[1]

[2]

v t e Tricyclics
Classes	Acridine Anthracene Dibenzazepine Dibenzocycloheptene Dibenzodiazepine Dibenzothiazepine Dibenzothiepin Dibenzoxazepine Dibenzoxepin Phenothiazine Pyridazinobenzoxazine Pyridinobenzodiazepine Thioxanthene
Antidepressants (TCAs and TeCAs)	7-OH-Amoxapine Amezepine Amineptine Amitriptyline Amitriptylinoxide Amoxapine Aptazapine Azepindole Azipramine Batelapine Butriptyline Cianopramine Ciclazindol Ciclopramine Cidoxepin Clomipramine Cotriptyline Cyanodothiepin Demexiptiline Depramine (balipramine) Desipramine (desmethylimipramine) Desmethylclomipramine Desmethyltrimipramine Dibenzepin Dimetacrine Dosulepin (dothiepin) Doxepin Enprazepine Esmirtazapine Fantridone Fluotracen Hepzidine Homopipramol Imipramine Imipraminoxide Intriptyline Iprindole Ketipramine Litracen Lofepramine Losindole Loxapine Maprotiline Mariptiline Mazindol Melitracen Metapramine Mezepine Mianserin Mirtazapine Monometacrine Naranol Nitroxazepine Norbutriptyline Nordoxepin Northiaden (nordosulepin) Nortriptyline (noramitriptyline) Noxiptiline Octriptyline Opipramol Oxaprotiline Pipofezine Pirandamine Propizepine Protriptyline Quinupramine Setiptiline (teciptiline) Spiroxepin Tandamine Tampramine Tianeptine Tienopramine Trimipramine
Antihistamines	Azatadine Bisulepin Clobenzepam Cyproheptadine Dacemazine Deptropine Desloratadine Epinastine Etymemazine Fenethazine Hydroxyethylpromethazine Isopromethazine Isothipendyl Ketotifen Latrepirdine Loratadine Mebhydrolin Mequitazine Methdilazine Olopatadine Oxomemazine Phenindamine Pimethixene Promethazine Propiomazine Rupatadine Thiazinamium
Antipsychotics	Acetophenazine Alimemazine Amoxapine Asenapine Butaclamol Butaperazine Carfenazine (carphenazine) Carpipramine Chlorpromazine Chlorprothixene Ciclindole Citatepine Clocapramine Clomacran Clorotepine Clotiapine Clozapine Cyanothepin Doclothepin Docloxythepin Erizepine Flucindole Flumezapine Fluotracen Flupentixol Fluphenazine Gevotroline Homopipramol Isofloxythepin Levomepromazine/Methotrimeprazine Loxapine Lurasidone Maroxepin Meperathiepin Mesoridazine Metiapine Metitepine Metoxepin Mosapramine Naranol Octomethothepin Olanzapine Oxyclothepin Oxyprothepin Pentiapine Peradithiepin Perathiepin Perazine Perphenazine Periciazine Pinoxepin Piperacetazine Pipotiazine Piquindone Prochlorperazine Promazine Prothipendyl Quetiapine Savoxepin/Cipazoxapine Sulforidazine Tenilapine Thiethylperazine Thiopropazate Thioridazine Thiothixene Tilozepine Traboxopine Trifluoperazine Triflupromazine Trifluthepin Zotepine Zuclopenthixol
Anticonvulsants	Carbamazepine Dizocilpine Eslicarbazepine Eslicarbazepine acetate Etazepine Licarbazepine Oxcarbazepine Oxitriptyline Rispenzepine
Others	Adosopine Aminopromazine Atiprosin Beloxepin Benzoctamine Carvedilol Cidoxepin Cyclobenzaprine Damotepine Darenzepine Elanzepine Fluradoline Methylene blue Monatepil Nuvenzepine Oxetorone Perlapine P7C3 Pinadoline Pirenzepine Pirolate Pitrazepin Pizotifen Profenamine Serazapine Siltenzepine Telenzepine Tipindole Tropatepine Zolenzepine

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Clinical data

ATC code	None
Legal status
Legal status	Not marketed
Identifiers
IUPAC name N-Methyl-2,3,7,8-tetrahydro-1H-quino[1,8-ab][1]benzazepin-3-amine
CAS Number	33545-56-1
PubChem CID	160410
ChemSpider	140965
UNII	BXS8X8APGS
ChEMBL	ChEMBL2105933
Chemical and physical data
Formula	C₁₈H₂₀N₂
Molar mass	264.372 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c14c2c(ccc1)C(NC)CCN2c3ccccc3CC4

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