Chemistry:Pinoxepin

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Short description: Chemical compound
Pinoxepin
Pinoxepin.svg
Clinical data
Other namesPinoxepine; P-5227
Routes of
administration		Oral
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC23H27ClN2O2
Molar mass398.93 g·mol−1
3D model (JSmol)

Pinoxepin (INN; developmental code name P-5227; pinoxepin hydrochloride (USAN)) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed.[1][2][3][4][5] It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine.[4] The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.[2][4]

References

  1. ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 984–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA984. 
  2. ↑ 2.0 2.1 Annual Reports in Medicinal Chemistry. Academic Press. 1 January 1967. pp. 2–. ISBN 978-0-08-058346-4. https://books.google.com/books?id=nnVxhG5GLXYC&pg=RA2-PR3. 
  3. ↑ Psychopharmacological Agents. Elsevier Science. 2 December 2012. pp. 102–. ISBN 978-0-323-15128-3. https://books.google.com/books?id=38QOitKplWgC&pg=PA102. 
  4. ↑ 4.0 4.1 4.2 Handbook of Psychopharmacology: Volume 10: Neoroleptics and Schizophrenia. Springer Science & Business Media. 6 December 2012. pp. 200–. ISBN 978-1-4613-4042-3. https://books.google.com/books?id=C97OBgAAQBAJ&pg=PT200. 
  5. ↑ Alterations of Metabolites in the Nervous System. Springer Science & Business Media. 11 November 2013. pp. 335–. ISBN 978-1-4757-6740-7. https://books.google.com/books?id=dYnSBwAAQBAJ&pg=PA335. 





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