Chemistry:N-Acetylmescaline

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N-Acetylmescaline
Acetylmescaline.svg
Names
Preferred IUPAC name
N-[2-(3,4,5-Trimethoxyphenyl)ethyl]acetamide
Identifiers
3D model (JSmol)
ChemSpider
Properties
C13H19NO4
Molar mass 253.298 g·mol−1
Melting point 93 to 94 °C (199 to 201 °F; 366 to 367 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

N-Acetylmescaline is a mescaline derivative found in trace quantities in peyote (Lophophora williamsii).[1] It is a metabolite of mescaline in humans, but it has little pharmacological effects of its own.[2] At doses of up to 750 mg, only mild drowsiness was observed.[2]

N-Acetylmescaline has microtubule assembly inhibitory activity.[3]

References

  1. Cite error: Invalid <ref> tag; no text was provided for refs named Buckingham
  2. 2.0 2.1 Maxwell Gordon, ed. Psychopharmacological Agents. 4. p. 94. 
  3. Dumortier, C; Potenziano, JL; Bane, S; Engelborghs, Y (1997). "The mechanism of tubulin-colchicine recognition--a kinetic study of the binding of a bicyclic colchicine analogue with a minor modification of the a ring". European Journal of Biochemistry 249 (1): 265–9. doi:10.1111/j.1432-1033.1997.t01-1-00265.x. PMID 9363778.