Chemistry:Trisescaline
Trisescaline (TRIS), also known as trescaline or as 3,4,5-triethoxyphenethylamine, is a chemical compound of the phenethylamine and scaline families related to mescaline.[1][2][3][4] It is the derivative of mescaline in which the three methoxy groups on the phenyl ring have been replaced with ethoxy groups.[1][2][3][4]
In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists trisescaline's dose as greater than 240 mg orally and its duration as unknown.[1][2][3] The drug produced no effects at tested doses of up to 240 mg orally.[1]
Trisescaline produced no psychedelic-like behavioral effects in cats even at very high doses.[1]
The chemical synthesis of trisescaline has been described.[1][4]
Trisescaline was first described in the scientific literature by Shulgin and Peyton Jacob III in 1984.[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]
See also
- Scaline
- TWEETIO § Scalines
- Thiotrisescaline
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. http://www.erowid.org/library/books_online/pihkal/pihkal.shtml. http://www.erowid.org/library/books_online/pihkal/pihkal175.shtml
- ↑ 2.0 2.1 2.2 "Structure-Activity Relationships of the Classic Hallucinogens and Their Analogs". Hallucinogens: An Update. National Institute on Drug Abuse Research Monograph Series. 146. National Institute on Drug Abuse. 1994. pp. 74–91. https://bibliography.maps.org/resources/download/11534.
- ↑ 3.0 3.1 3.2 "Basic Pharmacology and Effects". Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. 2003. pp. 67–137. ISBN 978-0-12-433951-4. https://bibliography.maps.org/resources/download/12634.
- ↑ 4.0 4.1 4.2 4.3 "Sulfur analogues of psychotomimetic agents. 3. Ethyl homologues of mescaline and their monothio analogues". J Med Chem 27 (7): 881–888. July 1984. doi:10.1021/jm00373a013. PMID 6737431.
External links
- TRIS (Trisescaline) - Isomer Design
- TRIS (Trisescaline) - Erowid
- TRIS (Trisescaline) - PiHKAL - Isomer Design
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