Chemistry:2,2'-Difluorofentanyl
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| Formula | C22H26F2N2O |
| Molar mass | 372.460 g·mol−1 |
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2,2'-Difluorofentanyl is an opioid analgesic that is an analog of fentanyl which has been sold as a designer drug.[2]
Side effects
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[3] A new wave of fentanyl analogues and associated deaths began in around 2014 in the US, and have continued to grow in prevalence; especially since 2016 these drugs have been responsible for hundreds of overdose deaths every week.[4]
Legal status
As a ring-substituted derivative of fentanyl, 2,2'-difluorofentanyl is banned under drug analog laws in the United States[1] and other jurisdictions around the world.[citation needed]
See also
References
- ↑ 1.0 1.1 "Schedules of Controlled Substances:Temporary Placement of Fentanyl-Related Substances in Schedule I. Temporary amendment; temporary scheduling order". Federal Register 83 (25): 5188–5192. February 2018. PMID 29932611.
- ↑ "The identification and analytical characterization of 2,2'-difluorofentanyl". Drug Testing and Analysis 10 (4): 774–780. April 2018. doi:10.1002/dta.2264. PMID 28851108.
- ↑ "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". The International Journal on Drug Policy 26 (7): 626–631. July 2015. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.
- ↑ "Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review". Neuropharmacology 134 (Pt A): 121–132. May 2018. doi:10.1016/j.neuropharm.2017.10.016. PMID 29042317. https://escholarship.org/uc/item/8xh0s7nf.
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