Chemistry:4-Chloroisobutyrylfentanyl
 | |
| Legal status | |
|---|---|
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| UNII | |
| Chemical and physical data | |
| Formula | C23H29ClN2O |
| Molar mass | 384.95 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
4-Chloroisobutyrylfentanyl (para-Chloroisobutyrylfentanyl, 4-Cl-iBF) is an opioid analgesic that is an analog of fentanyl,[1] and has been sold online as a designer drug.[2][3]
Side effects
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[4] A new wave of fentanyl analogues and associated deaths began in around 2014 in the US, and have continued to grow in prevalence; especially since 2016 these drugs have been responsible for hundreds of overdose deaths every week.[5]
Legal status
para-Chloroisobutyrylfentanyl has been a Schedule I controlled drug in the United States since 1 February 2018.[6] It was banned in Finland in September 2017,[7] and in Sweden in October 2017.[8]
See also
References
- ↑ "Studies on fentanyl and related compounds IV. Chromatographic and spectrometric discrimination of fentanyl and its derivatives". Journal of Analytical Toxicology 23 (4): 280–285. 1999. doi:10.1093/jat/23.4.280. PMID 10445491.
- ↑ Furanylfentanyl. Report on the risk assessment of N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide (furanylfentanyl) in the framework of the Council Decision on new psychoactive substances. EMCDDA Risk Assessments, 2017
- ↑ "Recent Deaths Possibly Linked to Fentanyl.". UK National Crime Agency. April 2017. http://www.nationalcrimeagency.gov.uk/publications/795-recent-deaths-possibly-linked-to-fentanyl/file.
- ↑ "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". The International Journal on Drug Policy 26 (7): 626–631. July 2015. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.
- ↑ "Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review". Neuropharmacology 134 (Pt A): 121–132. May 2018. doi:10.1016/j.neuropharm.2017.10.016. PMID 29042317. https://escholarship.org/uc/item/8xh0s7nf.
- ↑ "Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I". Federal Register. 1 February 2018. https://www.federalregister.gov/documents/2018/02/01/2018-02008/schedules-of-controlled-substances-temporary-placement-of-seven-fentanyl-related-substances-in.
- ↑ "Notification detail. Government Decree amending Annex IV to the Government Decree on substances, preparations and plants to be classified as narcotics The following 9 new substances are classified: 4-chloro-isobutyrfentanyl, 4-Fluoro-isobutyrfentanyl, 3-phenylpropanoylfentanyl, benzodioxole fentanyl, benzoyl fentanyl, cyclopentyl fentanyl, cyclopropyl fentanyl, methoxyacetyl fentanyl and tetramethylcyclopropyane fentanyl.". European Commission. 12 September 2017. http://ec.europa.eu/growth/tools-databases/tris/en/search/?trisaction=search.detail&year=2017&num=437.
- ↑ "14 nya ämnen kan klassas som narkotika eller hälsofarlig vara.". The Public Health Agency of Sweden. 14 October 2017. https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2017/oktober/14-nya-amnen-kan-klassas-som-narkotika-eller-halsofarlig-vara/.
 |  |
