Chemistry:Isotocyanozene

From HandWiki

Isotocyanozene (5-cyano-isotodesnitazene) is a benzimidazole opioid analogue of isotonitazene which has been sold as a designer drug.[1] It was first characterised by the drug checking service CanTEST, in September 2025 as an expected 'opioid' sample, and then later as an expected 'benzodiazepine' sample.[2][3] Its μ-opioid in vitro activity is close to that of fentanyl.[4] Following identification in human biological samples, isotocyanozene has been described to have opioid effects.[5]

See also

References

  1. "5-cyano Isotodesnitazene (hydrochloride)". https://www.caymanchem.com/product/43596/5-cyano-isotodesnitazene-hydrochloride. 
  2. "Community Notice 22nd of September 2025: Isotocyanozene found in 'opioid' capsule". CanTEST. Health and drug checking service, Canberra. September 2025. https://www.instagram.com/p/DO5XilJFBLr/?utm_source=ig_web_copy_link. 
  3. "Isotocyanozene found in 'opioid' capsule". The Know. 2025-09-22. https://theknow.org.au/alerts_warnings/isotocyanozene-found-in-opioid-capsule/. 
  4. "Identification of isotocyanozene at an Australian drug checking service". Forensic Chemistry 49. 2026-04-28. doi:10.1016/j.forc.2026.100744. 
  5. "Isotocyanozene: detection of the 5-cyano analog of isotonitazene in human biological samples". Clinical Toxicology 63 (9): 691–692. September 2025. doi:10.1080/15563650.2025.2528990. PMID 40625206.