Chemistry:Prodilidine
From HandWiki
Short description: Chemical compound
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| Formula | C15H21NO2 |
| Molar mass | 247.338 g·mol−1 |
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Prodilidine is an opioid analgesic which is a ring-contracted analogue of prodine. It has around the same analgesic efficacy as codeine, but is only around 1/3 the potency (100mg prodilidine is equivalent to 3mg oral morphine). It has little abuse potential.[1][2][3][4][5]
See also
References
- ↑ "Addictiveness of 1,2-dimethyl,3-phenyl,3-propionoxy pyrrolidine hydrochloride (ARC I-O-1)". UNODC Bulletin on Narcotics 16 (1): 37–43. January 1964. http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1964-01-01_1_page005.html.
- ↑ "Treatment of pain in patients with a new nonnarcotic analgesic, prodilidine hydrochloride (Cogesic)". Current Therapeutic Research, Clinical and Experimental 3: 472–7. November 1961. PMID 13915874.
- ↑ "The pharmacology of prodilidine hydrochloride, a new analgetic agent". The Journal of Pharmacology and Experimental Therapeutics 134: 332–40. December 1961. PMID 14456453.
- ↑ "Absorption, excretion and fate of prodilidine". The Journal of Pharmacology and Experimental Therapeutics 138: 392–8. December 1962. PMID 13999550.
- ↑ "Prodilidine Hydrochloride: A new moderately potent analgesic". The American Journal of the Medical Sciences 247: 62–8. January 1964. doi:10.1097/00000441-196401000-00009. PMID 14106881.
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