Chemistry:Prosidol

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Short description: Chemical compound
Prosidol
Prosidol.svg
Prosidol ball-and-stick.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC18H27NO3
Molar mass305.418 g·mol−1
3D model (JSmol)
  (verify)

Prosidol is an opioid analgesic that is an analogue of prodine. It was originally discovered by J.F. MacFarlan and Co. in the 1950s.[1] It was further developed in Russia in the 1990s during research into the related drug pethidine.[2]

Prosidol has seen some clinical use, but is still a relatively new drug and does not yet have an extensive history of use. It produces similar effects to other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.[3][4]

References

  1. "Piperidine compounds" US patent 2960507
  2. "[First experience in the use of a new Russian narcotic analgesic prosidol in oncology]" (in ru). Anesteziologiia I Reanimatologiia (4): 53–7. 1994. PMID 7802322. 
  3. "[The problem of opioid tolerance and dependence during clinical use thereof]" (in ru). Anesteziologiia I Reanimatologiia (4): 17–21. 1996. PMID 8975562. 
  4. "[Prosidol, an original Russian opioid, in the treatment of pain syndromes]" (in ru). Anesteziologiia I Reanimatologiia (5): 74–7. 2001. PMID 11757313.