Chemistry:Isotodesnitazene
From HandWiki
Isotodesnitazene is a benzimidazole derivative which has potent opioid effects, having approximately 75x the potency of morphine. While isotodesnitazene itself appears to have been only rarely sold as a designer drug, numerous closely related compounds such as metodesnitazene, etodesnitazene, protodesnitazene, butodesnitazene, isotonitazene, isotonitazepyne and isotocyanozene have all been sold on the illicit market, so the pharmacological and analytical properties of isotodesnitazene have also been studied in the expectation that it may similarly become prominent at some point.[1][2][3][4][5][6]
See also
References
- ↑ "Human metabolism of four synthetic benzimidazole opioids: isotonitazene, metonitazene, etodesnitazene, and metodesnitazene". Archives of Toxicology 98 (7): 2101–2116. July 2024. doi:10.1007/s00204-024-03735-0. PMID 38582802. Bibcode: 2024ArTox..98.2101T.
- ↑ "Nitazene test strips: a laboratory evaluation". Harm Reduction Journal 21 (1). August 2024. doi:10.1186/s12954-024-01078-8. PMID 39198843.
- ↑ "Discriminative stimulus and antinociceptive effects of sixteen nitazene analogs in rodents". Neuropharmacology 272. July 2025. doi:10.1016/j.neuropharm.2025.110416. PMID 40120927.
- ↑ "The UHPLC-MS/MS method for the determination of 26 synthetic benzimidazole opioids (nitazene analogs) with isomers separation". Journal of Pharmaceutical and Biomedical Analysis 260. August 2025. doi:10.1016/j.jpba.2025.116796. PMID 40068235.
- ↑ "Comparison of Activation Techniques for the Identification of Nitazene Analogs Using the NIST/NIJ Data Interpretation Tool". Rapid Communications in Mass Spectrometry 40 (5). March 2026. doi:10.1002/rcm.70004. PMID 41359886.
- ↑ Availability of nitazenes for purchase in Australia and internationally via cryptomarkets, September 2021 - August 2025 (Report). UNSW Sydney. 2025. doi:10.26190/unsworks/31698.
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