Chemistry:LY-88329
From HandWiki
Short description: Chemical compound
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| Formula | C22H27NO2 |
| Molar mass | 337.463 g·mol−1 |
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LY-88329 is an opioid receptor ligand related to medicines such as pethidine. It has high affinity to the μ-opioid receptor, but unlike structurally related drugs such as 3-methylfentanyl and OPPPP, LY-88329 is a potent opioid antagonist. In animal studies it blocks the effects of morphine and has anorectic action.[1][2]
See also
References
- ↑ "Behavioral effects of phenylpiperidine narcotic antagonists". Pharmacology, Biochemistry, and Behavior 15 (1): 65–70. July 1981. doi:10.1016/0091-3057(81)90340-3. PMID 7291232.
- ↑ "Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat". The Journal of Pharmacology and Experimental Therapeutics 253 (1): 85–9. April 1990. PMID 2329525.
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