Chemistry:Metodesnitazene

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Short description: Chemical compound
Metodesnitazene
Metodesnitazene.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
Chemical and physical data
FormulaC21H27N3O
Molar mass337.467 g·mol−1
3D model (JSmol)

Metodesnitazene (also known as Metazene) is a benzimidazole derivative with opioid effects, though unlike related compounds such as metonitazene and etodesnitazene which are many times more potent, metodesnitazene is only around the same potency as morphine in animal studies.[1][2][3][4][5] It was proposed by the DEA to be placed under legal control in the US in December 2021.[6]

See also

References

  1. "Benzimidazol-derivate und verwandte Heterocyclen. II. Synthese von 1-aminoalkyl-2-benzyl-benzimidazolen.". Helvetica Chimica Acta 43 (3): 800–809. 1960. doi:10.1002/hlca.19600430323. 
  2. "Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of nitazene new synthetic opioids.". Authorea. 12 November 2020. doi:10.22541/au.160520665.59016513/v1. 
  3. "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles". ACS Chemical Neuroscience 12 (7): 1072–1092. April 2021. doi:10.1021/acschemneuro.1c00037. PMID 33760580. 
  4. ""Etazene, safer than heroin and fentanyl": Non-fentanyl novel synthetic opioid listings on one darknet market". Drug and Alcohol Dependence 225: 108790. August 2021. doi:10.1016/j.drugalcdep.2021.108790. PMID 34091156. 
  5. "Development and Evaluation of a Synthetic Opioid Targeted Gas Chromatography Mass Spectrometry (GC-MS) Method.". Journal of Forensic Sciences 66 (6): 2369–2380. 2021. doi:10.33774/chemrxiv-2021-0pcnq. PMID 34459514. 
  6. "Schedules of Controlled Substances: Temporary Placement of Butonitazene, Etodesnitazene, Flunitazene, Metodesnitazene, Metonitazene, N-pyrrolidino etonitazene, and Protonitazene in Schedule I.". A Proposed Rule by the Drug Enforcement Administration. 7 December 2021. https://www.federalregister.gov/documents/2021/12/07/2021-26263/schedules-of-controlled-substances-temporary-placement-of-butonitazene-etodesnitazene-flunitazene.